Polarization-sensitive optical coherence tomography with angular compounding

Maxina Sheft; Georgia L. Jones; Bhaskara Rao Chintada; Néstor Uribe-Patarroyo; Brett Bouma; Martin Villiger

doi:10.1117/12.3005516

17 April 2024 Polarization-sensitive optical coherence tomography with angular compounding

Maxina Sheft, Georgia L. Jones, Bhaskara Rao Chintada, Néstor Uribe-Patarroyo, Brett Bouma, Martin Villiger

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC1283020 (2024) https://doi.org/10.1117/12.3005516
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) allows the visualization of biological tissue microstructure by measuring the pathlength difference, amplitude, and polarization of backscattered light. Speckle grains complicate the visualizations due to scattering structures in tissue smaller than the PS-OCT resolution. We developed an angular compounding system to reduce speckle by rotating samples and collecting tomograms at multiple imaging angles, without modifying PS-OCT hardware or optical pathways. Tomograms were acquired, aligned with affine transformations, and averaged. This method successfully reduced the speckle and improved visualization of intensity and birefringence images.

Conference Presentation

Citation Download Citation

Maxina Sheft, Georgia L. Jones, Bhaskara Rao Chintada, Néstor Uribe-Patarroyo, Brett Bouma, and Martin Villiger "Polarization-sensitive optical coherence tomography with angular compounding", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283020 (17 April 2024); https://doi.org/10.1117/12.3005516

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