At this moment, we are still far away from understanding many neurologic diseases. However, the emergence of different bioelectronic technologies opens the pathway to fathom them once and for all. Organic electrochemical transistors (OECTs) can assist here, thanks to their superior recording of neurological signals. Moreover, their flexible nature allows application in non-invasive scalp electrode devices. Nevertheless, the field of OECTs is still in its infancy, and clear, rational design criteria are lacking. Hence, dedicated backbone and side-chain engineering could enlighten the structure-performance relationships for next-generation conjugated polymers that are able to transport both ions and electrons in future OECTs.
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