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Breast tomosynthesis imaging configuration optimization based on computer simulation

[+] Author Affiliations
Shiyu Xu

Southern Illinois University, Department of Electrical and Computer Engineering, Carbondale, Illinois 62901

Linlin Cong

Southern Illinois University, Biomedical Engineering Graduate Program, Carbondale, Illinois 62901

Jianping Lu

The University of North Carolina, Department of Physics and Astronomy, and Curriculum in Applied Sciences and Engineering, Chapel Hill, North Carolina 27599

The University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina 27599

Otto Zhou

The University of North Carolina, Department of Physics and Astronomy, and Curriculum in Applied Sciences and Engineering, Chapel Hill, North Carolina 27599

The University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina 27599

Yueh Z. Lee

The University of North Carolina, Department of Radiology, Chapel Hill, North Carolina 27599

Ying Chen

Southern Illinois University, Department of Electrical and Computer Engineering, Carbondale, Illinois 62901

Southern Illinois University, Biomedical Engineering Graduate Program, Carbondale, Illinois 62901

J. Electron. Imaging. 23(1), 013017 (Feb 06, 2014). doi:10.1117/1.JEI.23.1.013017
History: Received February 19, 2013; Revised September 22, 2013; Accepted January 2, 2014
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Abstract.  Digital tomosynthesis is an innovative imaging technology for early breast cancer detection by providing three-dimensional anatomical information with fast image acquisition and low-dose radiation. Most of current breast tomosynthesis systems utilize a design where a single x-ray tube moves along an arc above objects over a certain angular range. The mechanical movement and patient motion during the scan may degrade image quality. With a carbon nanotube–based multibeam x-ray source, a new breast tomosynthesis modality is innovated, which will potentially produce better image quality with stationary beam sources and faster scan and it enables a variety of beam distributions. In this study, several beam distributions, such as beam sources spanning along a one-dimensional (1-D) parallel configuration and sources over a two-dimensional (2-D) rectangle shape are investigated based on computer simulations. Preliminary results show that 2-D rectangle shapes outperform 1-D parallel shapes by providing better Z-resolution, enhanced image contrast, reduced out-of-plane blur and artifacts and lower reconstruction noise. These benefits may expand tomosynthesis applications to diagnostic and interventional procedures.

© 2014 SPIE and IS&T

Citation

Shiyu Xu ; Linlin Cong ; Jianping Lu ; Otto Zhou ; Yueh Z. Lee, et al.
"Breast tomosynthesis imaging configuration optimization based on computer simulation", J. Electron. Imaging. 23(1), 013017 (Feb 06, 2014). ; http://dx.doi.org/10.1117/1.JEI.23.1.013017


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