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Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies

[+] Author Affiliations
Qirong Zhang, Yuhua Li, Ben Steele

University of Oklahoma, Center for Bioengineering and School of Electrical and Computer Engineering, Norman, Oklahoma 73019

Xizeng Wu

University of Alabama at Birmingham, Department of Radiology, Birmingham, Alabama 35233

Wei R. Chen

University of Central Oklahoma, Department of Physics and Engineering, Edmond, Oklahoma 73034 E-mail: wchen@ucok.edu

John Rong

University of Oklahoma Health Science Center, Department of Radiological Sciences, Oklahoma City, Oklahoma 73104

Hong Liu

University of Oklahoma, Center for Bioengineering and School of Electrical and Computer Engineering, Norman, Oklahoma 73019

J. Electron. Imaging. 14(2), 023002 (May 12, 2005). doi:10.1117/1.1902763
History: Received Jul. 23, 2004; Revised Oct. 21, 2004; Accepted Nov. 8, 2004; May 12, 2005; Online May 12, 2005
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The purpose of this study is to compare the performance of a complementary metal–oxide–semiconductor (CMOS)-based digital x-ray imaging system with that of a charge-coupled device (CCD)-based system for small animal research. A CMOS-based digital x-ray imaging system was developed and tested. The core of this system is a detector module consisting of eight joint CMOS chips, each having a size of 512×1024 pixels with a readout unit on the side. The pixel size of the CMOS detectors is 0.048 mm. The contrast detail detectability of the CMOS-based system was studied using different phantoms, and compared with that of a CCD-based digital imaging system. The contrast detail curves of the CMOS-based image system, obtained from the observer-based studies, are highly comparable to the CCD-based imaging system, particularly at higher x-ray exposures. The images of fine structures of a mouse, acquired by the CMOS system, demonstrated the capability of the system in the studies of small animals. With integration potential, manufacturability, and low costs, the CMOS-based imaging systems could be used in animal studies and potentially become useful clinical tools for diagnosis. © 2005 SPIE and IS&T.

© 2005 SPIE and IS&T

Citation

Qirong Zhang ; Yuhua Li ; Ben Steele ; Xizeng Wu ; Wei R. Chen, et al.
"Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies", J. Electron. Imaging. 14(2), 023002 (May 12, 2005). ; http://dx.doi.org/10.1117/1.1902763


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